Humanitas Research Hospital
Inflammation and Immunology in Cardiovascular Pathologies Lab
The group of Dr. Condorelli is interested in the molecular mechanisms of heart failure and, more broadly, of cardiovascular diseases. They study how genetics and epigenetics determine cardiovascular pathologies and, in particular, the roles of non-coding RNAs (microRNAs and, more recently, long-non coding RNAs) and histone and DNA modifications in different cardiovascular processes, in particular those affecting the myocardium.
Selected publications on lncRNA
Scavenger Receptors and Non-Coding RNAs: Relevance in Atherogenesis
Dai Y, Condorelli G, Mehta JL. Cardiovasc. Res.2016, 109(1):24-33.
Epigenetic modifications and noncoding RNAs in cardiac hypertrophy and failure
Condorelli G, Greco CM. Nat. Rev Cardiol. 2015, 12(8):488-97.
Long Noncoding RNAs and MicroRNAs in Cardivascular Pathopysiology
Thum T, Condorelli G. Circ Res. 2015, 116(4):751-7762.
Long noncoding RNA: a new player of heart failure?
Papait R, Kunderfranco P, Stirparo GG, Latronico MV, Condorelli G. J Cardiovasc Transl Res. 2013, 6(6):876-83.