Department of Cardiovascular Sciences, Laboratory of Experimental Cardiology
We aim to understand how the epigenome, including long non-coding and microRNAs, contributes to determining and maintaining the phenotype of the adult cardiac myocyte and how degradation/remodelling of the adult cardiac myocyte epigenome underlies phenotypic changes associated with disease and ageing.
- Gene expression analysis
- Cardiac myocyte nuclei isolation
- Small rodent modeling of cardiovascular disease and cardiac imaging
- Cardiac myocyte electrophysiology and calcium signalling
Interested in collaborating on
We are open to collaboration in all aspects of our work – most notably to gain greater expertise in analysis of deep RNA sequencing data to identify novel transcripts relevant to cardiac biology and disease.
Also structural (RNA) biology expertise – understanding/modelling secondary structures and interactomes.