Some of the collaborative projects within the network
Realising the therapeutic potential of novel cardioprotective therapies
Launched in July 2017, this Action aims improve the translation of novel cardioprotective therapies for patient benefit. It has four main objectives, each linked to a working group (WG):
- WG1: New targets – use innovative strategies to discover novel targets for cardioprotection
- WG2: Combination therapy – investigate the effects of combination therapy directed to multiple targets as an innovative cardioprotective strategy
- WG3: Confounders – use more clinically relevant animal models for testing novel cardioprotective therapies taking into account the confounding effects of co-morbidities and co-medication
- WG4: Consortium – set up a European network of research centers for:
- (a) Multi-center preclinical testing of novel cardioprotective therapies using small/large animal models of acute myocardial ischaemia/reperfusion injury;
- (b) Proof-of-concept clinical testing of novel cardioprotective therapies in acute myocardial patients
Cardiolinc members participating in the Action are Derek Hausenloy (Chair of the Action), Péter Ferdinandy (Vice Chair of the Action), David Erlinge, Monika Barteková, Przemyslaw Leszek, and Yvan Devaux.
COST Action preparation
Cardiolinc coordinator Yvan Devaux and his team from the Luxembourg Institute of Health prepared a COST Action aiming to advance research on the role of RNAs in cardiovascular disease. Even if you are not a Cardiolinc member, you can get involved. If you are interested in participating, please contact us and we will be happy to provide you with additional details and aims of the different working groups.
Cardiolinc members Firalis, Hannover Medical School and Luxembourg Institute of Health, together with the LifeSequencing company, secured funding through the Eurostars program for a 3-year project aiming at developing an in vitro diagnostic assay for prognostication of patients with acute myocardial infarction.