2018

Unravelling atherosclerotic heterogeneity by single cell RNA sequencing.
McCracken IR, Taylor RS, Henderson NC, Sluimer JC, Baker AH. Curr Opin Lipidol. 2018 Dec;29(6):488-489.

Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy. Morhenn K, Quentin T, Wichmann H, Steinmetz M, Prondzynski M, Söhren KD, Christ T, Geertz B, Schröder S, Schöndube FA, Hasenfuss G, Schlossarek S, Zimmermann WH, Carrier L, Eschenhagen T, Cardinaux JR, Lutz S, Oetjen E. J Mol Cell Cardiol. 2018 Dec 3.

Heart rate in heart failure with mid-range ejection fraction. Yılmaz MB. Anatol J Cardiol. 2018 Dec 6.

Vaccination of adults with heart failure and chronic heart conditions: Expert opinion. Çelik A, Altay H, Azap A, Çavuşoğlu Y, Nalbantgil S, Şenol E, Temizhan A, Yılmaz MB. Turk Kardiyol Dern Ars. 2018 Dec;46(8):723-734.

Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China. Büning H, Griesenbach U, Fehse B, Ylä-Herttuala S, Anagnou NP, van Beusechem V, Raya A, Verhoeyen E. Hum Gene Ther. 2018 Dec 4.

Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis. Huang J, Kelly CP, Bakirtzi K, Villafuerte Gálvez JA, Lyras D, Mileto SJ, Larcombe S, Xu H, Yang X, Shields KS, Zhu W, Zhang Y, Goldsmith JD, Patel IJ, Hansen J, Huang M, Yla-Herttuala S, Moss AC, Paredes-Sabja D, Pothoulakis C, Shah YM, Wang J, Chen X. Nat Microbiol. 2018 Dec 3.

Remote ischaemic preconditioning in isolated aortic valve and coronary artery bypass surgery: a randomized trial. Moscarelli M, Fiorentino F, Suleiman MS, Emanueli C, Reeves BC, Punjabi PP, Angelini GD. Eur J Cardiothorac Surg. 2018 Dec 12.

Cold Ischemia Score: An mRNA Assay for the Detection of Extended Cold Ischemia in Formalin-fixed, Paraffin-embedded Tissue. Mathieson W, Mommaerts K, Trouet JM, Mathay C, Guan P, Carithers LJ, Rohrer D, Valley DR, Blanski A, Jewell S, Moore HM, Betsou F. J Histochem Cytochem. 2018 Dec 18:22155418819967.

Before the Pump. Norris DM, Santoro MM. Arterioscler Thromb Vasc Biol. 2018 Dec;38(12):2763-2764.

Non-Coding RNAs to Aid in Neurological Prognosis after Cardiac Arrest. Salgado-Somoza A, Stefanizzi FM, Stammet P, Erlinge D, Friberg H, Nielsen N, Devaux Y. Noncoding RNA. 2018 Dec 18;4(4). pii: E42.

A Novel PITX2c Gain-of-Function Mutation, p.Met207Val, in Patients With Familial Atrial Fibrillation Mechakra A, Footz T, Walter M, Aránega A, Hernández-Torres F, Morel E, Millat G, Yang YQ, Chahine M, Chevalier P, Christé G. Am J Cardiol. 2018 Dec 3. pii: S0002-9149(18)32152-0.

Updates in heart failure: what last year brought to us. Dinatolo E, Sciatti E, Anker MS, Lombardi C, Dasseni N, Metra M. ESC Heart Fail. 2018 Dec;5(6):989-1007.

Dietary antioxidant intake decreases carotid intima media thickness in women but not in men: A cross-sectional assessment in the Kardiovize study. Maugeri A, Hruskova J, Jakubik J, Kunzova S, Sochor O, Barchitta M, Agodi A, Bauerova H, Medina-Inojosa JR, Vinciguerra M. Free Radic Biol Med. 2018 Dec 18. pii: S0891-5849(18)31757-X.

DNA methylation processes in atheosclerotic plaque. Aavik E, Babu M, Ylä-Herttuala S. Atherosclerosis. 2018 Dec 18. pii: S0021-9150(18)31526-0.

Mean arterial pressure during targeted temperature management and renal function after out-of-hospital cardiac arrest. Grand J, Hassager C, Winther-Jensen M, Rundgren M, Friberg H, Horn J, Wise MP, Nielsen N, Kuiper M, Wiberg S, Thomsen JH, Jaeger Wanscher MC, Frydland M, Kjaergaard J. J Crit Care. 2018 Dec 18;50:234-241.

Circulating blood cells and extracellular vesicles in acute cardioprotection. Davidson SM, Andreadou I, Barile L, Birnbaum Y, Cabrera-Fuentes HA, Cohen MV, Downey JM, Girao H, Pagliaro P, Penna C, Pernow J, Preissner KT, Ferdinandy P. Cardiovasc Res. 2018 Dec 24.

SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4. Lyu Q, Xu S, Lyu Y, Choi M, Christie CK, Slivano OJ, Rahman A, Jin ZG, Long X, Xu Y, Miano JM. Proc Natl Acad Sci U S A. 2018 Dec 24. pii: 201810729.

Discovery profiling and bioinformatics analysis of serum microRNA in Mitochondrial NeuroGastroIntestinal Encephalomyopathy (MNGIE). Levene M, Enguita FJ, Bax BE. Nucleosides Nucleotides Nucleic Acids. 2018 Dec 27:1-12.

Adrenomedullin in heart failure: pathophysiology and therapeutic application. Voors AA, Kremer D, Geven C, Ter Maaten JM, Struck J, Bergmann A, Pickkers P, Metra M, Mebazaa A, Düngen HD, Butler J. Eur J Heart Fail. 2018 Dec 28.

EkoSonic Endovascular System for patients with acute pulmonary embolism and contraindication to systemic fibrinolysis. Visco E, Adamo M, Locantore E, Fiorina C, Chizzola G, Branca L, Abbenante A, Castiello A, Metra M, Curello S, Ettori F. J Cardiovasc Med (Hagerstown). 2018 Dec 24.

New insights into the haemo- and coelo-microbiota with antimicrobial activities from Echinodermata and Mollusca. Offret C, Jégou C, Mounier J, Fleury Y, Le Chevalier P. J Appl Microbiol. 2018 Dec 26.

Long non-coding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN. Hu YW, Guo FX, Xu YJ, Li P, Lu ZF, McVey DG, Zheng L, Wang Q, Ye JH, Kang CM, Wu SG, Zhao JJ, Ma X, Yang Z, Fang FC, Qiu YR, Xu BM, Xiao L, Wu Q, Wu LM, Ding L, Webb TR, Samani NJ, Ye S. J Clin Invest. 2018 Dec 27. pii: 98230.

Protein bioavailability of Wolffia globosa duckweed, a novel aquatic plant, - A randomized controlled trial. Kaplan A, Zelicha H, Tsaban G, Yaskolka Meir A, Rinott E, Kovsan J, Novack L, Thiery J, Ceglarek U, Burkhardt R, Willenberg A, Tirosh A, Cabantchik I, Stampfer MJ, Shai I. Clin Nutr. 2018 Dec 11. pii: S0261-5614(18)32577-9.

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Franceschini N, Giambartolomei C, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, Nolte IM, Lu L, Scholz M, Sargurupremraj M, Pitkänen N, Franzén O, Joshi PK, Noordam R, Marioni RE, Hwang SJ, Musani SK, Schminke U, Palmas W, Isaacs A, Correa A, Zonderman AB, Hofman A, Teumer A, Cox AJ, Uitterlinden AG, Wong A, Smit AJ, Newman AB, Britton A, Ruusalepp A, Sennblad B, Hedblad B, Pasaniuc B, Penninx BW, Langefeld CD, Wassel CL, Tzourio C, Fava C, Baldassarre D, O'Leary DH, Teupser D, Kuh D, Tremoli E, Mannarino E, Grossi E, Boerwinkle E, Schadt EE, Ingelsson E, Veglia F, Rivadeneira F, Beutner F, Chauhan G, Heiss G, Snieder H, Campbell H, Völzke H, Markus HS, Deary IJ, Jukema JW, de Graaf J, Price J, Pott J, Hopewell JC, Liang J, Thiery J, Engmann J, Gertow K, Rice K, Taylor KD, Dhana K, Kiemeney LALM, Lind L, Raffield LM, Launer LJ, Holdt LM, Dörr M, Dichgans M, Traylor M, Sitzer M, Kumari M, Kivimaki M, Nalls MA, Melander O, Raitakari O, Franco OH, Rueda-Ochoa OL, Roussos P, Whincup PH, Amouyel P, Giral P, Anugu P, Wong Q, Malik R, Rauramaa R, Burkhardt R, Hardy R, Schmidt R, de Mutsert R, Morris RW, Strawbridge RJ, Wannamethee SG, Hägg S, Shah S, McLachlan S, Trompet S, Seshadri S, Kurl S, Heckbert SR, Ring S, Harris TB, Lehtimäki T, Galesloot TE, Shah T, de Faire U, Plagnol V, Rosamond WD, Post W, Zhu X, Zhang X, Guo X, Saba Y; MEGASTROKE Consortium, Dehghan A, Seldenrijk A, Morrison AC, Hamsten A, Psaty BM, van Duijn CM, Lawlor DA, Mook-Kanamori DO, Bowden DW, Schmidt H, Wilson JF, Wilson JG, Rotter JI, Wardlaw JM, Deanfield J, Halcox J, Lyytikäinen LP, Loeffler M, Evans MK, Debette S, Humphries SE, Völker U, Gudnason V, Hingorani AD, Björkegren JLM, Casas JP, O'Donnell CJ. Nat Commun. 2018 Dec 3;9(1):5141.

The Emerging Role of the ADAMTS Family in Vascular Diseases. Rienks M, Barallobre-Barreiro J, Mayr M. Circ Res. 2018 Dec 7;123(12):1279-1281.

Role of miRNA in the Regulatory Mechanisms of Estrogens in Cardiovascular Ageing. Pérez-Cremades D, Mompeón A, Vidal-Gómez X, Hermenegildo C, Novella S. Oxid Med Cell Longev. 2018 Dec 20;2018:6082387.

December

November

Identification and regulation of the long non-coding RNA Heat2 in heart failure
Boeckel, J.-N., M. F. Perret, S. F. Glaser, T. Seeger, A. W. Heumüller, W. Chen, D. John, K. E. Kokot, H. A. Katus, J. Haas, M. K. Lackner, E. Kayvanpour, N. Grabe, C. Dieterich, S. von Haehling, N. Ebner, S. Hünecke, F. Leuschner, S. Fichtlscherer, B. Meder, A. M. Zeiher, S. Dimmeler and T. Keller. Journal of Molecular and Cellular Cardiology. 2018. Nov 13. pii: S0022-2828(18)30386-9.

Noncoding RNAs in acute kidney injury
Brandenburger T, Salgado Somoza A, Devaux Y, Lorenzen JM. Kidney Int. 2018, 94(5):870-881.

Inhibition of profibrotic microRNA-21 affects platelets and their releasate.
Barwari T, Eminaga S, Mayr U, Lu R, Armstrong PC, Chan MV, Sahraei M, Fernández-Fuertes M, Moreau T, Barallobre-Barreiro J, Lynch M, Yin X, Schulte C, Baig F, Pechlaner R, Langley SR, Zampetaki A, Santer P, Weger M, Plasenzotti R, Schosserer M, Grillari J, Kiechl S, Willeit J, Shah AM, Ghevaert C, Warner TD, Fernández-Hernando C, Suárez Y, Mayr M. JCI Insight. 2018 Nov 2;3(21). pii: 123335.

Circular RNAs in Muscle Function and Disease.
Greco S, Cardinali B, Falcone G, Martelli F. Int J Mol Sci. 2018 Nov 3;19(11). pii: E3454.

Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel JN, Perret MF, Glaser SF, Seeger T, Heumüller AW, Chen W, John D, Kokot KE, Katus HA, Haas J, Lackner MK, Kayvanpour E, Grabe N, Dieterich C, von Haehling S, Ebner N, Hünecke S, Leuschner F, Fichtlscherer S, Meder B, Zeiher AM, Dimmeler S, Keller T. J Mol Cell Cardiol. 2018 Nov 13. pii: S0022-2828(18)30386-9.

Circulating levels of microRNA 423-5p are associated with 90 day mortality in cardiogenic shock. Jäntti T, Segersvärd H, Tolppanen H, Tarvasmäki T, Lassus J, Devaux Y, Vausort M, Pulkki K, Sionis A, Bayes-Genis A, Tikkanen I, Lakkisto P, Harjola VP. ESC Heart Fail. 2018 Nov 24.

ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. Gould RA, Aziz H, Woods CE, Seman-Senderos MA, Sparks E, Preuss C, Wünnemann F, Bedja D, Moats CR, McClymont SA, Rose R, Sobreira N, Ling H, MacCarrick G, Kumar AA, Luyckx I, Cannaerts E, Verstraeten A, Björk HM, Lehsau AC, Jaskula-Ranga V, Lauridsen H, Shah AA, Bennett CL, Ellinor PT, Lin H, Isselbacher EM, Cardenas CLL, Butcher JT, Hughes GC, Lindsay ME; Baylor-Hopkins Center for Mendelian Genomics; MIBAVA Leducq Consortium, Mertens L, Franco-Cereceda A, Verhagen JMA, Wessels M, Mohamed SA, Eriksson P, Mital S, Van Laer L, Loeys BL, Andelfinger G, McCallion AS, Dietz HC. Nat Genet. 2018 Nov 19.

Description of Cardiological Apps From the German App Store: Semiautomated Retrospective App Store Analysis. Albrecht UV, Hasenfuß G, von Jan U. JMIR Mhealth Uhealth. 2018 Nov 20;6(11):e11753

circtools - a one-stop software solution for circular RNA research. Jakobi T, Uvarovskii A, Dieterich C. Bioinformatics. 2018 Nov 21.

November 2018 at a glance: from prediction of heart failure in asymptomatic subjects to advanced chronic heart failure. Metra M. Eur J Heart Fail. 2018 Nov;20(11):1503-1504.

Molecular insights into genome-wide association studies of chronic kidney disease-defining traits. Xu X, Eales JM, Akbarov A, Guo H, Becker L, Talavera D, Ashraf F, Nawaz J, Pramanik S, Bowes J, Jiang X, Dormer J, Denniff M, Antczak A, Szulinska M, Wise I, Prestes PR, Glyda M, Bogdanski P, Zukowska-Szczechowska E, Berzuini C, Woolf AS, Samani NJ, Charchar FJ, Tomaszewski M. Nat Commun. 2018 Nov 22;9(1):4800.

A step closer to improving cardiac homing of adipose-derived mesenchymal stem cells. LeBlanc AJ, Uchida S. Am J Physiol Heart Circ Physiol. 2018 Nov 21.

Echocardiographic diastolic function evolution in patients with an anterior Q-wave myocardial infarction: insights from the REVE-2 study. Ferreira JP, Bauters C, Eschalier R, Lamiral Z, Fay R, Huttin O, Girerd N, Zannad F, Pinet F, Rossignol P. ESC Heart Fail. 2018 Nov 20.

Diabetes Mellitus: Is It Protective against Aneurysm? A Narrative Review. Patel K, Zafar MA, Ziganshin BA, Elefteriades JA. Cardiology. 2018 Nov 19;141(2):107-122.

Molecular insights into genome-wide association studies of chronic kidney disease-defining traits. Xu X, Eales JM, Akbarov A, Guo H, Becker L, Talavera D, Ashraf F, Nawaz J, Pramanik S, Bowes J, Jiang X, Dormer J, Denniff M, Antczak A, Szulinska M, Wise I, Prestes PR, Glyda M, Bogdanski P, Zukowska-Szczechowska E, Berzuini C, Woolf AS, Samani NJ, Charchar FJ, Tomaszewski M. Nat Commun. 2018 Nov 22;9(1):4800.

Comparison of different chemically modified inhibitors of miR-199b in vivo. Duygu B, Juni R, Ottaviani L, Bitsch N, Wit JBM, de Windt LJ, da Costa Martins PA. Biochem Pharmacol. 2018 Nov 16. pii: S0006-2952(18)30490-8.

Long Non-Coding RNA Modulation of VEGF-A during Hypoxia. Moreau PR, Örd T, Downes NL, Niskanen H, Bouvy-Liivrand M, Aavik E, Ylä-Herttuala S, Kaikkonen MU. Noncoding RNA. 2018 Nov 20;4(4).

Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells. Nieminen T, Scott TA, Lin FM, Chen Z, Yla-Herttuala S, Morris KV. Front Cardiovasc Med. 2018 Nov 5;5:159.

CRISPR/Cas9 and p53: An Odd Couple Requiring Relationship Management. Ylä-Herttuala S. Mol Ther. 2018 Nov 16. pii: S1525-0016(18)30536-7.

LncRNA Meg3 protects endothelial function by regulating the DNA damage response. Shihabudeen Haider Ali MS, Cheng X, Moran M, Haemmig S, Naldrett MJ, Alvarez S, Feinberg MW, Sun X. Nucleic Acids Res. 2018 Nov 22.

The function of miR-143, miR-145 and the MiR-143 host gene in cardiovascular development and disease. Vacante F, Denby L, Sluimer JC, Baker AH. Vascul Pharmacol. 2018 Nov 28. pii: S1537-1891(18)30212-X.

Therapeutic effects of rosuvastatin in hypercholesterolemic prediabetic mice in the absence of low density lipoprotein receptor. Gurzeler E, Aavik E, Laine A, Valkama T, Niskanen H, Huusko J, Kaikkonen MU, Ylä-Herttuala S. Biochim Biophys Acta Gen Subj. 2018 Nov 30. pii: S0304-4165(18)30361-1.

Targeting Non-coding RNA in Vascular Biology and Disease. Hung J, Miscianinov V, Sluimer JC, Newby DE, Baker AH. Front Physiol. 2018 Nov 22;9:1655.

miR-212/132 Cluster Modulation Prevents Doxorubicin-Mediated Atrophy and Cardiotoxicity. Gupta SK, Garg A, Avramopoulos P, Engelhardt S, Streckfuss-Bömeke K, Batkai S, Thum T. Mol Ther. 2018 Nov 13. pii: S1525-0016(18)30539-2.

Exosomes: Basic Biology and Technological Advancements Suggesting Their Potential as Ischemic Heart Disease Therapeutics. Shanmuganathan M, Vughs J, Noseda M, Emanueli C. Front Physiol. 2018 Nov 19;9:1159.

Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure. Raso A, Dirkx E, Philippen LE, Fernandez-Celis A, De Majo F, Sampaio-Pinto V, Sansonetti M, Juni R, El Azzouzi H, Calore M, Bitsch N, Olieslagers S, Oerlemans MIFJ, Huibers MM, de Weger RA, Reckman YJ, Pinto YM, Zentilin L, Zacchigna S, Giacca M, da Costa Martins PA, López-Andrés N, De Windt LJ. Mol Ther. 2018 Nov 17. pii: S1525-0016(18)30547-1.

What Would You Do With a £30 Million Research Grant? Avkiran M, Samani NJ. Circ Res. 2018 Nov 9;123(11):1196-1198.

Decision-making algorithm for ascending aortic aneurysm: Effectiveness in clinical application? Saeyeldin A, Zafar MA, Li Y, Tanweer M, Abdelbaky M, Gryaznov A, Brownstein AJ, Velasquez CA, Buntin J, Thombre K, Ma WG, Erben Y, Rizzo JA, Ziganshin BA, Elefteriades JA. J Thorac Cardiovasc Surg. 2018 Nov 14. pii: S0022-5223(18)32927-1.

Surprisingly good results from a complex, lengthy aortic arch technique. Elefteriades JA, Zafar MA, Papanikolaou D, Ziganshin BA. J Thorac Cardiovasc Surg. 2018 Nov 15. pii: S0022-5223(18)32963-5.

Analysis of Cell Type-Specific Effects of MicroRNA-92a Provides Novel Insights Into Target Regulation and Mechanism of Action. Rogg EM, Abplanalp WT, Bischof C, John D, Schulz MH, Krishnan J, Fischer A, Poluzzi C, Schaefer L, Bonauer A, Zeiher AM, Dimmeler S. Circulation. 2018 Nov 27;138(22):2545-2558.

Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure. Dorsheimer L, Assmus B, Rasper T, Ortmann CA, Ecke A, Abou-El-Ardat K, Schmid T, Brüne B, Wagner S, Serve H, Hoffmann J, Seeger F, Dimmeler S, Zeiher AM, Rieger MA. JAMA Cardiol. 2018 Dec 19.

Clinical Phenotype and Genotype Associations With Improvement in Left Ventricular Function in Dilated Cardiomyopathy. Verdonschot JAJ, Hazebroek MR, Wang P, Sanders-van Wijk S, Merken JJ, Adriaansen YA, van den Wijngaard A, Krapels IPC, Brunner-La Rocca HP, Brunner HG, Heymans SRB. Circ Heart Fail. 2018 Nov;11(11):e005220.

Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery. Aragam KG, Chaffin M, Levinson RT, McDermott G, Choi SH, Shoemaker MB, Haas ME, Weng LC, Lindsay ME, Smith JG, Newton-Cheh C, Roden DM, London B, Wells QS, Ellinor PT, Kathiresan S, Lubitz SA; GRADE Investigators. Circulation. 2018 Nov 11.

Hematopoietic Deficiency of the Long Non-Coding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation. Cremer S, Michalik KM, Fischer A, Pfisterer L, Jaé N, Winter C, Boon RA, Muhly-Reinholz M, John D, Uchida S, Weber C, Poller W, Günther S, Braun T, Li DY, Maegdefessel L, Matic Perisic L, Hedin U, Soehnlein O, Zeiher A, Dimmeler S. Circulation. 2018 Nov 28.

Plasma levels of apolipoproteins C-III, A-IV, and E are independently associated with stable atherosclerotic cardiovascular disease. Dittrich J, Beutner F, Teren A, Thiery J, Burkhardt R, Scholz M, Ceglarek U. Atherosclerosis. 2018 Nov 9;281:17-24.

Coronary Microvascular Injury in Reperfused Acute Myocardial Infarction: A View From an Integrative Perspective. Sezer M, van Royen N, Umman B, Bugra Z, Bulluck H, Hausenloy DJ, Umman S. J Am Heart Assoc. 2018 Nov 6;7(21):e009949.

In Aptamers They Trust: The Caveats of the SOMAscan Biomarker Discovery Platform from SomaLogic. Joshi A, Mayr M. Circulation. 2018 Nov 27;138(22):2482-2485.

Decision-making algorithm for ascending aortic aneurysm: Effectiveness in clinical application? Saeyeldin A, Zafar MA, Li Y, Tanweer M, Abdelbaky M, Gryaznov A, Brownstein AJ, Velasquez CA, Buntin J, Thombre K, Ma WG, Erben Y, Rizzo JA, Ziganshin BA, Elefteriades JA. J Thorac Cardiovasc Surg. 2018 Nov 14. pii: S0022-5223(18)32927-1.

Incidence and impact of prosthesis-patient mismatch following transcatheter aortic valve implantation. Seoudy H, Güßefeld N, Frank J, Freitag-Wolf S, Lutter G, Eden M, Rangrez AY, Kuhn C, Frey N, Frank D. Clin Res Cardiol. 2018 Nov 19.

October

Circular RNAs in Blood
Vea A, Llorente-Cortes V, de Gonzalo-Calvo D. Adv Exp Med Biol. 2018, 1087:119-130.

A new "lnc" between non-coding RNA and cardiac regeneration
Meloni M, Riley PR, Baker AH. Cardiovasc Res. 2018, 114(12):1569-1570.

A novel murine model for arrhythmogenic cardiomyopathy points to a pathogenic role of Wnt signaling and miRNA dysregulation Calore M, Lorenzon A, Vitiello L, Poloni G, Khan MAF, Beffagna G, Dazzo E, Sacchetto C, Polishchuk R, Sabatelli P, Doliana R, Carnevale D, Lembo G, Bonaldo P, De Windt L, Braghetta P, Rampazzo A. Cardiovasc Res. 2018.

Circulating miR-1254 predicts ventricular remodeling in patients with ST-Segment-Elevation Myocardial Infarction: A cardiovascular magnetic resonance study. de Gonzalo-Calvo D, Cediel G, Bär C, Núñez J, Revuelta-Lopez E, Gavara J, Ríos-Navarro C, Llorente-Cortes V, Bodí V, Thum T, Bayes-Genis A. Sci Rep. 2018, 8(1):15115.

Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease. Ackers-Johnson M, Tan WLW, Foo RS. Nat Commun. 2018 Oct 30;9(1):4434.

ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb. Blackwood EA, Hofmann C, Santo Domingo M, Bilal AS, Sarakki A, Stauffer WT, Arrieta A, Thuerauf DJ, Kolkhorst FW, Müller OJ, Jakobi T, Dieterich C, Katus HA, Doroudgar S, Glembotski CC. Circ Res. 2018 Oct 19.

What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Guzik TJ, Antoniades C, Baker AH, Harrison DG, Loughrey CM, Maffia P, Murphy E, Nicklin SA, Peter K, Pearson J, Casadei B. Cardiovasc Res. 2018 Oct 1;114(12):1565-1568.

August

Long non-coding RNA H19 regulates endothelial cell aging via inhibition of Stat3 signaling
Hofmann P, Sommer J, Theodorou K, Kirchhof L, Fischer A, Li Y, Perisic L, Hedin U, Maegdefessel L, Dimmeler S, Boon RA. Cardiovasc Res. 2018.

Immune system-mediated atherosclerosis caused by deficiency of long noncoding RNA MALAT1 in ApoE-/- mice
Gast M, Rauch BH, Nakagawa S, Haghikia A, Jasina A, Haas J, Nath N, Jensen L, Stroux A, Böhm A, Friebel J, Rauch U, Skurk C, Blankenberg S, Zeller T, Prasanth KV, Meder B, Kuss A, Landmesser U, Poller W. Cardiovasc Res. 2018.

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection
Bøtker HE, Hausenloy D, Andreadou I, Antonucci S, Boengler K, Davidson SM, Deshwal S, Devaux Y, Di Lisa F, Di Sante M, Efentakis P, Femminò S, García-Dorado D, Giricz Z, Ibanez B, Iliodromitis E, Kaludercic N, Kleinbongard P, Neuhäuser M, Ovize M, Pagliaro P, Rahbek-Schmidt M, Ruiz-Meana M, Schlüter KD, Schulz R, Skyschally A, Wilder C, Yellon DM, Ferdinandy P, Heusch G. Basic Res Cardiol. 2018, 113(5):39.

Cyclin dependent kinase inhibitor 1 C is a female-specific marker of left ventricular function after acute myocardial infarction
Lalem T, Zhang L, Scholz M, Burkhardt R, Saccheti V, Teren A, Thiery J, Devaux Y; Cardiolinc™ network (www.cardiolinc.org). Int J Cardiol. 2018. pii: S0167-5273(18)32556-7.

MicroRNA-24 and the Diabetic Heart
Rienks M, Joshi A, Mayr M. JACC Basic Transl Sci. 2018, 3(3):363-365.

RNA therapeutics for heart disease
De Majo F, De Windt LJ. Biochem Pharmacol. 2018, 155:468-478.

LncRNAs Coming of Age
Grote P, Boon RA. Circ Res. 2018, 123(5):535-537.

July

The association between plasma miR-122-5p release pattern at admission and all-cause mortality or shock after out-of-hospital cardiac arrest
Gilje P, Frydland M, Bro-Jeppesen J, Dankiewicz J, Friberg H, Rundgren M, Devaux Y, Stammet P, Al-Mashat M, Jögi J, Kjaergaard J, Hassager C, Erlinge D. Biomarkers. 2018, 1-25.

Plasma microRNAs as biomarkers for Lamin A/C-related dilated cardiomyopathy
Toro R, Blasco-Turrión S, Morales-Ponce FJ, Gonzalez P, Martínez-Camblor P, López-Granados A, Brugada R, Campuzano O, Pérez-Serra A, Rosa Longobardo F, Mangas A, Llorente-Cortes V, de Gonzalo-Calvo D. J Mol Med (Berl). 2018.

MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium
Ágg B, Baranyai T, Makkos A, Vető B, Faragó N, Zvara Á, Giricz Z, Veres DV, Csermely P, Arányi T, Puskás LG, Varga ZV, Ferdinandy P. Sci Rep. 2018, 8(1):10134.

MicroRNA-199a-3p and MicroRNA-199a-5p Take Part to a Redundant Network of Regulation of the NOS (NO Synthase)/NO Pathway in the Endothelium
Joris V, Gomez EL, Menchi L, Lobysheva I, Di Mauro V, Esfahani H, Condorelli G, Balligand JL, Catalucci D, Dessy C. Arterioscler Thromb Vasc Biol. 2018, pii: ATVBAHA.118.311145.

RNA Therapeutics in Cardiovascular Disease
Lucas T, Bonauer A, Dimmeler S. Circ Res. 2018, 123(2):205-220.

MicroRNA-155 Amplifies Nitric Oxide/cGMP Signaling and Impairs Vascular Angiotensin II Reactivity in Septic Shock
Vasques-Nóvoa F, Laundos TL, Cerqueira RJ, Quina-Rodrigues C, Soares-Dos-Reis R, Baganha F, Ribeiro S, Mendonça L, Gonçalves F, Reguenga C, Verhesen W, Carneiro F, Paiva JA, Schroen B, Castro-Chaves P, Pinto-do-Ó P, Nascimento DS, Heymans S, Leite-Moreira AF, Roncon-Albuquerque R Jr. Crit Care Med. 2018.

June

Circular RNAs: a novel tool in cardiovascular biomarker development?
Vea A, Llorente-Cortes V, de Gonzalo-Calvo DNon-coding RNA Investigation. 2018.

Non-coding RNAs in aneurysmal aortopathy
Spin JM, Li DY, Maegdefessel L, Tsao PS. Vascul Pharmacol. 2018, pii: S1537-1891(17)30367-1.

Extracellular Vesicle Crosstalk Between the Myocardium and Immune System Upon Infarction
Burnap SA, Mayr M. Circ Res. 2018, 123(1):15-17.

miR-210 Enhances the Therapeutic Potential of Bone-Marrow-Derived Circulating Proangiogenic Cells in the Setting of Limb Ischemia
Besnier M, Gasparino S, Vono R, Sangalli E, Facoetti A, Bollati V, Cantone L, Zaccagnini G, Maimone B, Fuschi P, Da Silva D, Schiavulli M, Aday S, Caputo M, Madeddu P, Emanueli C, Martelli F, Spinetti G. Mol Ther. 2018, pii: S1525-0016(18)30262-4.

Study Design and qPCR Data Analysis Guidelines for Reliable Circulating miRNA Biomarker Experiments: A Review
de Ronde MWJ, Ruijter JM, Moerland PD, Creemers EE, Pinto-Sietsma SJ. Clin Chem. 2018, pii: clinchem.2017.285288.

A systems immunology approach identifies the collective impact of 5 miRs in Th2 inflammation
Kılıç A, Santolini M, Nakano T, Schiller M, Teranishi M, Gellert P, Ponomareva Y, Braun T, Uchida S, Weiss ST, Sharma A, Renz H. JCI Insight. 2018, 3(11). pii: 97503.

Long Non-coding RNAs in Endothelial Biology
Weirick T, Militello G, Uchida S. Front Physiol. 2018, 9:522.

Expanding the horizons of microRNA bioinformatics
Huntley RP, Kramarz B, Sawford T, Umrao Z, Kalea AZ, Acquaah V, Martin MJ, Mayr M, Lovering RC. RNA. 2018, pii: rna.065565.118.

Non-coding RNAs in vascular disease – from basic science to clinical applications: Scientific update from the Working Group of Myocardial Function of the European Society of Cardiology
Fiedler J, Baker AH, Dimmeler S, Heymans S, Mayr M, Thum T. Cardiovasc Res. 2018.

Lnc'ing Ca2+, SERCA and cardiac disease
Vervliet T, Robinson EL, Roderick HL. Cell Calcium. 2018, pii: S0143-4160(18)30086-1.

Cardiac-specific research platforms engender novel insights into mitochondrial dynamism. Dorn GW 2nd. Curr Opin Physiol. 2018 Jun;3:110-115.

May

Vascular extracellular vesicles in comorbidities of heart failure with preserved ejection fraction in men and women: The hidden players. A mini review
Gohar A, de Kleijn DPV, Hoes AW, Rutten FH, Hilfiker-Kleiner D, Ferdinandy P, Sluijter JPG, den Ruijter HM. Vascul Pharmacol. 2018, pii: S1537-1891(17)30466-4.

Non-coding RNAs and exercise: pathophysiological role and clinical application in the cardiovascular system
Gomes CPC, de Gonzalo-Calvo D, Toro R, Fernandes T, Theisen D, Wang D-ZDevaux Y; on behalf of the Cardiolinc™ network. Clin Sci. 2018, 132(9)925-942.

Circulating microRNAs as emerging cardiac biomarkers responsive to acute exercise
de Gonzalo-Calvo D, Dávalos A, Fernández-Sanjurjo M, Amado-Rodríguez L, Díaz-Coto S, Tomás-Zapico C, Montero A, García-González Á, Llorente-Cortés V, Heras ME, Boraita Pérez A, Díaz-Martínez ÁE, Úbeda N, Iglesias-Gutiérrez E. Int J Cardiol. 2018, 264:130-136.

MicroRNA-221/222 Expression in Atherosclerotic Coronary Artery Plaque and Peripheral Blood
Bildirici AE, Arslan S, Özbilüm Şahin N, Berkan Ö, Beton O, Yılmaz MB. Biomarkers. 2018, 8:1-19.

A Breath of Fresh Air(n) in Molecular Cardiology: Airn Long Noncoding RNA Regulates Cardiomyocyte Resistance to Stress and Igf2bp2 Translation
Greco S, Martelli F. Circ Res. 2018, 122(10):1321-1323.

Airn Regulates Igf2bp2 Translation in Cardiomyocytes
Hosen MR, Militello G, Weirick T, Ponomareva Y, Dassanayaka S, Moore JB 4th, Döring C, Wysoczynski M, Jones SP, Dimmeler S, Uchida SCirc Res. 2018, 122(10):1347-1353.

April

Analysis of the microRNA signature in left atrium from patients with valvular heart disease reveals their implications in atrial fibrillation
Doñate Puertas R, Jalabert A, Meugnier E, Euthine V, Chevalier P, Rome S. PLoS One. 2018, 13(5):e0196666.

RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling
van den Hoogenhof MM, Beqqali A, Amin AS, van der Made I, Aufiero S, Khan MA, Schumacher CA, Remme CA, Backs J, Verkerk AO, Baartscheer A, Pinto YMCreemers EECirculation. 2018.

miR-22 in Smooth Muscle Cells: A Potential Therapy for Cardiovascular Disease
Huang ZP, Wang DZ. Circulation. 2018, 137(17):1842-1845.

Circulating non-coding RNAs in biomarker-guided cardiovascular therapy: a novel tool for personalised medicine?
de Gonzalo-Calvo D, Vea A, Bär C, Fiedler J, Couch L, Brotons C, Llorente-Cortés V, Thum T. European Heart Journal. 2018.

Long Non-Coding RNAs in Vascular Inflammation
Haemmig S, Simion V, Feinberg MW. Front Cardiovasc Med. 2018.

H19 Induces Abdominal Aortic Aneurysm Development and Progression
Li DY, Busch A, Jin H, Chernogubova E, Pelisek J, Karlsson J, Sennblad B, Liu S, Lao S, Hofmann P, Bäcklund A, Eken SM, Roy J, Eriksson P, Dacken B, Ramanujam D, Dueck A, Engelhardt S, Boon RA, Eckstein HH, Spin JM, Tsao PS, Maegdefessel L. Circulation. 2018.

Mirna-Mediated Mechanisms of Cardiac Protection in Ischemic and Remote Ischemic Preconditioning - A Qualitative Systematic Review
Kohns M, Huhn R, Bauer I, Brandenburger T. Shock. 2018.

A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1
Militello G, Hosen MR, Ponomareva Y, Gellert P, Weirick T, John D, Hindi SM, Mamchaoui K, Mouly V, Döring C, Zhang L, Nakamura M, Kumar A, Fukada SI, Dimmeler S, Uchida S. J Mol Cell Biol. 2018.

March

UHRF1 epigenetically orchestrates smooth muscle cell plasticity in arterial disease
Elia L, Kunderfranco P, Carullo P, Vacchiano M, Farina FM, Hall IF, Mantero S, Panico C, Papait R, Condorelli G, Quintavalle M. J Clin Invest. 2018.

MicroRNA-21 and the Vulnerability of Atherosclerotic Plaques
Barwari T, Rienks M, Mayr M. Mol Ther. 2018.

Cardiac circRNAs arise mainly from constitutive exons rather than alternatively spliced exons
Aufiero S, van den Hoogenhof MMG, Reckman YJ, Beqqali A, van der Made I, Kluin J, Khan MAF, Pinto YM, Creemers EE. RNA. 2018.

Epigenetic modulation of vascular diseases: Assessing the evidence and exploring the opportunities
Schiattarella GG, Madonna R, Van Linthout S, Thum T, Schulz R, Ferdinandy P, Perrino C. Vascul Pharmacol. 2018.

The long noncoding RNA landscape in cardiovascular disease: a brief update
Salamon I, Saccani Jotti G, Condorelli G. Curr Opin Cardiol. 2018.

Redefining biomarkers in heart failure
Correale M, Monaco I, Brunetti ND, Di Biase M, Metra M, Nodari S, Butler J, Gheorghiade M; Master Program Students on Drug Development for Heart Failure. Heart Fail Rev. 2018.

An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm
Lino Cardenas CL, Kessinger CW, Cheng Y, MacDonald C, MacGillivray T, Ghoshhajra B, Huleihel L, Nuri S, Yeri AS, Jaffer FA, Kaminski N, Ellinor P, Weintraub NL, Malhotra R, Isselbacher EM, Lindsay ME. Nat Commun. 2018, 9(1):1009.

Non-coding RNAs as therapeutic targets for preventing myocardial ischemia-reperfusion injury
Ong SB, Katwadi K, Kwek XY, Ismail NI, Chinda K, Ong SG, Hausenloy DJ. Expert Opin Ther Targets. 2018, 22(3):247-261.

Circular RNAs in the cardiovascular system
Gomes CPC, Salgado-Somoza A, Creemers EE, Dieterich C, Lustrek M, Devaux Y; on behalf of the Cardiolinc™ networkNon-Coding RNA Res. 2018, 3(1):1-11.

3-gene panel improves the prediction of left ventricular dysfunction after acute myocardial infarction
Boileau A, Lalem T, Vausort M, Zhang L, Devaux Y; Cardiolinc™ network (www.cardiolinc.org). Int J Cardiol. 2018, 254:28-35.

February

MicroRNA as Crucial Regulators of Gene Expression in Estradiol-Treated Human Endothelial Cells
Vidal-Gómez X, Pérez-Cremades D, Mompeón A, Dantas AP, Novella S, Hermenegildo C. Cell Physiol Biochem. 2018, 45(5):1878-1892.

Endogenous Heparin Interferes with Quantification of MicroRNAs by RT-qPCR
Boileau A, Lino Cardenas CL, Lindsay ME, Devaux Y; Cardiolinc™ network. Clin Chem. 2018, 64(5):863-865. 

Airn Regulates Igf2bp2 Translation in Cardiomyocytes
Hosen MR, Militello G, Weirick TM, Ponomareva Y, Dassanayaka S, Moore JB, Doering C, Wysoczynski M, Jones SP, Dimmeler S, Uchida S. Circ Res. 2018, pii: CIRCRESAHA.117.312215.

Pathophysiological understanding of HFpEF: microRNAs as part of the puzzle
Rech M, Barandiaran Aizpurua A, van Empel V, Van Bilsen M, Schroen B. Cardiovasc Res. 2018.

LncRNAs in vascular biology and disease
Simion V, Haemmig S, Feinberg MW. Vascul Pharmacol. 2018, pii: S1537-1891(17)30441-X.

Decreased FENDRR and LincRNA-p21 expression in atherosclerotic plaque
Çekin N, Özcan A, Göksel S, Arslan S, Pınarbaşı E, Berkan Ö. Anatol J Cardiol. 2018, 19(2):131-136.

miRNA as a New Regulatory Mechanism of Estrogen Vascular Action
Pérez-Cremades D, Mompeón A, Vidal-Gómez X, Hermenegildo C, Novella S. Int J Mol Sci. 2018, 19(2). pii: E473.

RNA Editing: Unexplored Opportunities in the Cardiovascular System
Uchida S, Jones SP. Circ Res. 2018, 122(3):399-401.

January

Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions
Jin H, Li DY, Chernogubova E, Sun C, Busch A, Eken SM, Saliba-Gustafsson P, Winter H, Winski G, Raaz U, Schellinger IN, Simon N, Hegenloh R, Matic LP, Jagodic M, Ehrenborg E, Pelisek J, Eckstein HH, Hedin U, Backlund A, Maegdefessel L. Mol Ther. 2018.

Circulating Circles Predict Postoperative Atrial Fibrillation
Reckman YJ, Creemers EE. J Am Heart Assoc. 2018, 7(2). pii: e008261.

Localization of transcripts, translation, and degradation for spatiotemporal sarcomere maintenance
Lewis YE, Moskovitz A, Mutlak M, Heineke J, Caspi LH, Kehat I. J Mol Cell Cardiol. 2018, S0022-2828(18)30021-X.

The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2
Neumann P, Jaé N, Knau A, Glaser SF, Fouani Y, Rossbach O, Krüger M, John D, Bindereif A, Grote P, Boon RA, Dimmeler SNat Commun. 2018, 16;9(1):237.

Deep Computational Circular RNA Analytics from RNA-seq Data
Jakobi T, Dieterich CMethods Mol Biol. 2018, 1724:9-25.