University of Edinburgh
Centre for Cardiovascular Science, Queen's Medical Research Institute
Andrew H Baker
We are interested in the development of novel interventions in the context of vascular repair and regeneration in the cardiovascular system, using gene therapy and modification of non-coding RNA. We are interested in bypass grafting, coronary stenting, pulmonary hypertension and related complications. Particular interests are in the field of miRNA and long non-coding RNA.
- Animal models of vascular pathology – mouse and pig
- miRNA and lncRNA expertise
Interested in collaborating on
Complimentarity in animal models and mechanisms of lncRNA function and regulation.
Selected publications on lncRNA
A Role for the Long Noncoding RNA SENCR in Commitment and Function of Endothelial Cells
Boulberdaa M, Scott E, Ballantyne M, Garcia R, Descamps B, Angelini GD, Brittan M, Hunter A, McBride M, McClure J, Miano JM, Emanueli C, Mills NL, Mountford JC, Baker AH. Mol Ther. 2016, 24(5):978-90.
Smooth muscle enriched long non-coding RNA (SMILER) regulates cell proliferation
Ballantyne, MD, Dakin R, Pinel K, Vesey AT, Diver L, Mackenze R, Garcia R, Welsh P, Sattar N, Hamilton G, Joshi N, Dweck MR, Miano JM, Newby DE, McDonald RA, Baker AH. Circulation. 2015, 133(21):2050-65.