University of Münster
Institute of Human Genetics, Genetic Epidemiology
The genetic epidemiology group at the Institute of Human Genetics, University of Muenster, focusses on the genetic underpinnings of complex cardiovascular diseases. By analyzing genomic variants and their interactions with epigenetic data layers using systems genetics approaches, we aim to undertstand the molecular networks contributing to cardiovascular diseases. We believe that long non-coding RNAs represent a promising source for a new generation of cardiovascular biomarkers.
We have an interdisciplinary team of researchers supported by a powerful Illumina-based core facility to design, perform and analyze complex genome-wide studies based on next generation sequencing or microarray-based experiments.
Interested in collaborating on
We are looking for expertise in lncRNA structure prediction especially in combination with next generation sequencing approaches and integrative data analysis strategies. We are also looking for collaborations with partners who provide experimental model systems to investigate the functional effects of genetic variants in lncRNAs.
Selected publications on ncRNA and cardiovascular disease
Rühle F, Stoll M. Long non-coding RNA Databases in Cardiovascular Research. Genomics Proteomics Bioinformatics. 2016, 14(4):191-9.